Pycnogenol (150 mg/day) reduced pain in a study of 100 people with osteoarthritis after 3 months. . 2005 - 2023 WebMD LLC. In another good study, 48 patients with diabetes and high blood pressure on ACE inhibitors were randomized to receive either Pycnogenol 125 mg daily or placebo for 12 weeks. Sort By. From diabetes and sexual function to sports performance and beautiful skin, pine bark extract may be worth exploring to provide results youre looking to achieve. Some studies also suggest it can help guard against coronary artery disease and blood clots, per webmd.com. (8). Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. Dr. Steven Lamm did a great job at explaining the new benefits of pycnogenol. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. The results showed that the combination of local and systemic applications of Pycnogenol were the best in terms of ulcer healing even though local application of Pycnogenol also speeded up ulcer healing. Almost 400 years later, Dr. Jacques Masquelier from France came across Cartiers account and started to look for the active ingredients from the bark of the tree. Additionally, athletes have endured less cramping and muscle pain when using the extract. The antibacterial activity was assessed indicating that the essential oil of pine bark, specifically the proanthocyanidins, were effective against P. aeruginosa, significantly inhibiting its growth. Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. Align your health hacks with your genes for optimal health & cognitive function. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. (4). Berberine is a compound extracted from several plants. ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". Pycnogenol is thought to be an antioxidant that helps protect cells from damage. These wounds occur most frequently in hospitals or in those with weakened immune systems, such as after surgery. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. The positive improvements in symptoms were greater among those taking Pycnogenol. There is limited evidence that it could be used in treating Attention Deficit Hyperactivity Disorder (ADHD). Pine bark extract has been studied regarding its relationship to exercise performance, oxidative stress and inflammation to body that has been imposed by exercise. A good-quality study was conducted in 77 diabetic patients who received their standard antidiabetic treatment along with 100 mg Pycnogenol a day or placebo for 12 weeks. In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. These benefits appeared to persist for some time even after stopping supplementation [72]. In contrast, almost 20% of the participants on inhalers alone had to increase their dosage. Diabetes-associated small blood vessel changes is the leading cause of diabetic ulcers. 2005 - 2023 WebMD LLC. Clearer skin, healthier hair there are a lot of claims about the health benefits of biotin. Various studies, referenced at uofmhealth.org, have shown that a daily dosage of Pycnogenol . It can also be used for local application on the skin without the risk of side effects. In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. Extracts can also be made from other pine barks, such as Pinus radiata, Pinus densiflora, Pinus thunbergii, and Pinus massoniana. Learn about this tree-based pill and how it might be able to help you. $31.99. DOI: Luzzi R, et al. Required fields are marked *. Add to Cart. Boost gastrointestinal health. In 24 people with early eye damage from diabetes, Pycnogenol improved vision, reduced eye swelling, and improved circulation in the eye after 2 months. Pycnogenol health benefits. Pycnogenol seems to help with asthma and allergies. There have been a variety of health benefits linked to beta glucan, specifically with the beta-1 3d glucan form which has more biological activity than other types of polysaccharides. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Start with a low dose so you can be sure it doesnt cause any side effects. PQQ (pyrroloquinoline quinone), also called methoxatin, is a vitamin-like compound that exists naturally in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk . Pine bark extract provides many benefits to the skin, including reducing the signs of aging. 10 Day Erection Delay Sex Pills. Regardless, a natural option is available and far worth the wait. Dr. Drew explains the benefits of probiotics for the gut microbiome and talks about the rise of leaky gut, and Dr. Steve shares how emotional stress can have real physical effects on the heart. Pycnogenol is a substance taken from the pine bark of trees found in the southwest region of France. All of our content is written by scientists and people with a strong science background. In one study, 200 mg a day of Pycnogenol taken three hours prior to the first cigarette for the day for two months significantly reduced cigarette-induced platelet aggregation. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. However, it's always a good idea to start with a low dose so you can monitor how your body responds. If you choose to use Pycnogenol, follow the dosage instructions on the label. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Score one for diabetes control and fewer risk factors for the heart. A clinical trial of 60 health professionals found that Pycnogenol (150 mg/day) may improve cognitive function, attention, mental performance and specific professional skills after 12 weeks. Enzogenol, a slightly different pine bark extract, may help improve brain function after mild concussions. According to the lab results of 10 volunteers, a higher Pycnogenol dose (300 mg) may impact these enzymes after just 30 minutes [52]. The study participants symptoms started to return a month after they stopped taking pine bark extract. Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. This can cause pain, especially in areas of the body that are used repeatedly, like your hands, fingers, and knees. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. Instead, use plain water to wipe yourself and then dry your bottom afterward. New research shows . WebMD does not provide medical advice, diagnosis or treatment. COPD. However, with the addition of twice-daily Pycnogenol, normal erection increased to 80%, which further increased to 92.5% during the third month on thrice-daily Pycnogenol. The Benefits of DIM. Dizziness. We take a look at what the science actually says. Interactions. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. What Are These Tiny Red Spots on My Skin (Petechiae)? You can gradually increase how much you take once you get a better idea of how your body reacts to it. Pycnogenol reduced foot swelling in 79% of the patients, versus one percent in the placebo group. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Organika Pycnogenol 50mg 50 Tablets . However, research on these two groups is limited [71, 15]. Lowers Blood Pressure. It also slightly decreased blood pressure and increased testosterone [67]. Pycnogenol is a patented extract of the French maritime pine bark (Pinus pinaster). Results failed to show any efficacy of Pycnogenol or methylphenidate when compared to placebo. Pycnogenol and Pine Bark Extract Supplements. Consider pine bark extract through a conversation with your physician or a functional medicine doctor. Another group of men who took just l-arginine didnt improve [66]. It may cause side effects such as: Risks. A 2021 review in the Arab Journal of Urology listed it first among "promising herbal remedies" for ED. Millions are hospitalized each year for . Can Pycnogenol help? The flesh of the grape contains approximately 1/20th-1/100th of the total antioxidant capacity of the seed or the skin. There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. . Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. It also appeared to improve their attention span, visual motor skills, and concentration. A study of 30 women found that Pycnogenol (75 mg/day) may reduce the skin area affected by melasma as well as lower symptoms of fatigue, constipation, body pain, and anxiety [62]. SelfDecode is a personalized health report service, Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. Purity and potency of Pycnogenolare continuously monitored . While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. Video: Why You Need Zinc and Where to Find It. It seems to lower blood pressure and improve blood flow to the legs. (7). It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. If possible, try to get pine bark extract from a local supplier, such as a health food store. Twenty-one patients were given Pycnogenol at 150 mg daily and 18 patients received no treatment for a period of eight weeks. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. Perimenopausal women who took pine bark extract for eight weeks noticed decreased cholesterol and triglyceride levels. Cigarette smoking increases platelet aggregation. The crew fell extremely ill from scurvy, an extreme lack of vitamin C. Cartiers crew crossed paths with a Quebec Indian who encouraged them to drink a tea made from pine bark and needles.